There are basically two types of OTC pain relievers. Some contain acetaminophen and others contain non-steroidal anti-inflammatory drugs (NSAIDs), according to the FDA, U.S. Food and Drug Administration.
Acetaminophen and NSAID's are used to treat many conditions such as headache, muscle aches, arthritis, backache, toothaches, colds and fevers. You may see acetaminophen under the name of Tylenol®. Examples of NSAID's are aspirin, ibuprofen, naproxen, and ketoprofen. These drugs have had to be given separately, typically at different time intervals.
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AFT Pharmaceuticals, a privately owned company with operations in both Australia and New Zealand, released the world's first combination analgesic in October 2009. Maxigesic® provides superior pain relief after oral surgery to acetaminophen or ibuprofen alone, according to NCBI, the National Center of Biotechnology Information. Maxigesic® tablets combine the two medications, acetaminophen and ibuprofen, in clinically appropriate doses to simplify administration and dosage regimen.
Department of Anaesthesiology at the University of Auckland, the Department of Anaesthesia at Auckland City Hospital, the Oral Health Unit at Greenlane Clinical Centre, the Oral and Maxillofacial Service at Quay Park Medical Centre, and the Department of Medicine at Christchurch School of Medicine and Health Sciences at the University of Otago all in New Zealand got together for this study, supported by AFT Pharmaceuticals Ltd., and they determined that doctors treating pain after oral surgery, in hospital and at home, and probably pain in many other situations, should consider using acetaminophen and ibuprofen together four times a day, provided there are no contraindications to either drug, and taking into account the known risks of NSAIDs. The combination formulation of Maxigesic simplifies this regimen.
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